Manipulating the intestinal microbiome in early life-implications for health outcomes

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Dr. Kelly Grzywacz, MD, FRCPC
University of Montreal

Dr. Kelly Grzywacz received her BSc in Physiology at McGill University. She went on to attend the University of Montreal's medical program. Dr. Grzywacz did her Pediatric residency at A.I. DuPont Hospital for Children, Wilmington,DE, Jefferson Medical College, in Philadelphia, PA and a Pediatric Gastroenterology Fellowship at CHU Sainte Justine. She then completed a Master's degree in Biochemistry from the University of Ottawa, studying the intestinal microbiome of premature infants receiving probiotics and lactoferrin. She is currently a Staff Gastroenterologist in the division of Pediatric Gastroenterology Hepatology and Nutrition at the CHU Sainte Justine.

Presentation Overview/Abstract

In recent years, scientists have begun to refute the long held belief that the womb is a sterile environment. In fact bacteria have been isolated from placenta, umbilical cord blood, amniotic fluid, and fetal membranes of healthy full term infants. Current evidence therefore suggests that the fetus might be exposed to bacteria even prior to passage through the birth canal, although direct experimental proofs of live microbes are still missing.
Studies have shown that there is an evolution of bacteria in full term neonatal intestines, which follows successive steps. During the first 6 months of life, Bifidobacterium remains one of the most predominant bacteria. Many changes occur in the first year of life followed by a stabilization of the microbiota, which parallels the transition to solid food, and the weaning of breast milk.

***Original Source: "2017 Thematic Conference", Saturday, January 14, 2017

Length: 28:53

Type: Video

Last Updated: February 2, 2017